Author

Diane Beuzelin

ORCID 0000-0003-4208-2633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Organism:non-human primate· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Andréa Romette· 2 shared Aude Faucon· 2 shared Bastien SERRANO· 2 shared Christophe FraisieriD· 2 shared Cléa Boursery· 2 shared Gauthier Dangla-PélissieriD· 2 shared Géraldine Ferracci· 2 shared Gersande Godefroy· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Andréa Romette

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMay 22, 2026

Harnessing TfR1 for Cross-Species Systemic Delivery of siRNAs to Deep Brain Regions Using Single-Domain Antibodies

Guillaume Jacquot, Marion David, Belinda Pecqueux…·Michel Khrestchatisky

This paper demonstrates the use of TfR1-targeting single-domain antibodies to deliver siRNAs systemically to deep brain regions, achieving efficient knockdown at low doses.

1 citation

mousenon-human primate

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NeuroscienceJournal of Controlled ReleasePeer-reviewedOct 17, 2025

Novel VHH targeting a unique TfR1 epitope for efficient cross-species delivery of drugs in the CNS

Marion David, Romy Cohen, Diane Beuzelin…·Michel Khrestchatisky

This study identifies cross-species reactive VHHs targeting a novel TfR1 epitope, enabling efficient BBB crossing for CNS drug delivery.

8 citations

mouserat

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