Simon Fristed Eskildsen

This study investigates a rodent model with an OGT-ID variant, revealing neurodevelopmental defects and behavioural abnormalities linked to O-GlcNAc dyshomeostasis.

This study investigates OGA inhibition as a potential therapy for OGT-CDG by creating a mouse model and showing partial restoration of O-GlcNAc homeostasis.

This study shows that reduced BRD1 function in minipigs leads to coordinated neurodevelopmental and metabolic changes in both brain and peripheral tissues.

This study uses MRI and diffusion kurtosis imaging to examine morphological and microstructural changes in the striatum and thalamus of individuals with crack cocaine addiction compared to controls, while considering age and cocaine use duration.