Author

Tue Fryland

Aarhus UniversityORCID 0000-0001-8083-992XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Anders Dupont BørglumiD· 2 shared Arne Mørk· 2 shared Gregers WegeneriD· 2 shared Jane ChristenseniD· 2 shared Jens Randel NyengaardiD· 2 shared Per QvistiD· 2 shared Aage Kristian Olsen AlstrupiD· 1 shared Anca StoicaiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersGenetics

Anders Dupont BørglumORCID

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3 papers

Recent·Most cited

BRD1 haploinsufficiency disrupts neurodevelopmental and metabolic homeostasis in a translational minipig model

Julie Grinderslev Donskov, Tue Fryland, Bolette Hestbek Nicolaisen, Sanne Hage la Cour, Paula Rodrigo Martin, Steffi Pauwels, Lina Zühlsdorf, Dimitrios Pediotidis-Maniatis, Jacob Egemose Høgfeldt, Arne Mørk, Jane Christensen, Ida E. Holm, Gregers Wegener, Simon Fristed Eskildsen, Torben E. Lund, , Per Qvist

This study shows that reduced BRD1 function in minipigs leads to coordinated neurodevelopmental and metabolic changes in both brain and peripheral tissues.

bioRxiv · Oct 21, 2025 · PreprintGenetics

Synergistic Effect of Serotonin 1A and Serotonin 1B/D Receptor Agonists in the Treatment of L-DOPA-Induced Dyskinesia in 6-Hydroxydopamine-Lesioned Rats

Mikael Søndergård Thomsen, Anca Stoica, Kenneth Vielsted Christensen, Tue Fryland, Jens Damsgaard Mikkelsen, John Bondo Hansen

This study evaluates the efficacy and safety of 5-HT1A and 5-HT1B/D agonists in reducing L-DOPA-induced dyskinesia in a rat model, finding synergistic effects and superior performance compared to amantadine.

Experimental Neurology · Aug 18, 2022Peer-reviewedNeuroscience

The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

Anto Praveen Rajkumar, Per Qvist, Sanne Hage Larsen, Ross M Lazarus, Jonatan Pallesen, Nicoletta Nava, Gudrun Winther, Nico Liebenberg, Veerle Paternoster, Tue Fryland, Johan Palmfeldt, Kim Fejgin, Arne Mørk, Mette Nyegaard, Bente Pakkenberg, , Anders Dupont Børglum

This study investigates the role of BRD1 in sex-biased nuclear receptor signaling and its implications in mental disorders using mouse models and gene expression analysis.

bioRxiv · Apr 7, 2018 · PreprintNeuroscience