Cancer BiologybioRxivPreprint
Diet-induced changes in the colonic microenvironment reduce polyp development in APCMin/+Msh2-/- mice by triggering ER stress
María López Chiloeches, A. Belcheva
The paper shows that two diets reduce CRC development in APCMin/+Msh2-/- mice by inducing ER stress and enhancing barrier function through upregulation of Muc-2 and heat shock proteins.
DOI 10.1101/2025.03.13.643056