Author

John C. Bramley

Washington University in St. LouisORCID 0000-0003-4312-5279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Colin L. KremitzkiiD· 2 shared Jason E. WaligorskiiD· 2 shared Jeffrey MilbrandtiD· 2 shared Maria A. VakakiiD· 2 shared Robi David MitraiD· 2 shared Vinay D. ChandrasekaraniD· 2 shared William BuchseriD· 2 shared Alex L. YenkiniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenetics

Colin L. KremitzkiORCID

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2 papers

Recent·Most cited

Geneticsnpj ImagingPeer-reviewedAug 1, 2025

Pathogenic Morphological Signatures of Perturbations in Mitochondrial-Related Genes Revealed by Pooled Imaging Assay

Colin L. Kremitzki, Jason E. Waligorski, Graham W. Bachman…·William Buchser

The paper identifies mitochondrial-related genes critical for morphology using a pooled imaging assay and reveals pathogenic variants associated with mitochondrial aggregation.

2 citations

humanimaging

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 12, 2021

Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen

Alex L. Yenkin, John C. Bramley, Colin L. Kremitzki…·William Buchser

The paper introduces Raft-Seq, a functional genomics platform that distinguishes pathogenic MFN2 mutations using high-content imaging, machine learning, and microraft isolation.

1 citation

humanimaging

𝕏 PostBluesky