Author

Gwendal Dujardin

University of OxfordORCID 0000-0003-4320-6351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Rui Sousa‐LuísiD· 2 shared Adrian R. KraineriD· 1 shared Alberto Rodolfo KornblihttiD· 1 shared Carika WeldoniD· 1 shared Hiroshi KimurâiD· 1 shared Inna ZukheriD· 1 shared José N. Stigliano· 1 shared Luciano E. MarascoiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Rui Sousa‐LuísORCID

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2 papers

Recent·Most cited

Molecular BiologyCellPeer-reviewedJun 1, 2022

Towards a combined therapy for spinal muscular atrophy based on opposing effects of an antisense oligonucleotide on chromatin and splicing

Luciano E. Marasco, Gwendal Dujardin, Rui Sousa‐Luís…·Alberto Rodolfo Kornblihtt

The paper shows that combining an ASO with HDAC inhibitors enhances SMN2 exon 7 inclusion in SMA mice, improving SMN expression and function.

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mouseexperimental assay

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GenomicsMolecular CellPeer-reviewedMar 18, 2021

POINT Technology Illuminates The Processing Of Polymerase-Associated Intact Nascent Transcripts

Rui Sousa‐Luís, Gwendal Dujardin, Inna Zukher…·Takayuki Nojima

The paper introduces POINT technology to study co-transcriptional RNA processing, revealing insights into splicing kinetics, Xrn2 exonuclease specificity, and transcript termination mechanisms.

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