Author

David H. Beier

University of MichiganORCID 0000-0003-4333-5831Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew JiangiD· 1 shared Bhairavi SrinageshwariD· 1 shared Brigitte Demelo· 1 shared Diane E. LucenteiD· 1 shared Esaria OliveriD· 1 shared Eunhye LeeiD· 1 shared Faaiza Saif· 1 shared Ihn Sik SeongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Andrew JiangORCID

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2 papers

Recent·Most cited

BiophysicsBiophysical JournalPeer-reviewedSep 10, 2026

Localized ribosome access and distal tuning via the Listeria prfA RNA thermometer

Martin R. O’Steen, Jocelyn V. Chen, David H. Beier…·Sarah C. Keane

This study investigates the temperature-dependent unfolding mechanism of the Listeria prfA RNA thermometer, revealing how structural changes at the ribosome binding site and upper helix regulate translation.

DOI 10.1016/j.bpj.2026.09.005

bacteria (other)experimental assay

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GeneticsProceedings of the National Academy of SciencesPeer-reviewedMar 2, 2026

Huntington's disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion

Eunhye Lee, Wonju Kim, David H. Beier…·Ihn Sik Seong

This paper investigates the protective effect of the LIG1 K845N variant in Huntington's disease by showing it increases ligase fidelity and suppresses somatic CAG repeat expansion.

DOI 10.1073/pnas.2518854123

mouseexperimental assay

𝕏 PostBluesky