Helen C. Lai

The paper uses spatial transcriptomics and multiomic profiling to identify sex-specific neuron types and their functional roles in the mouse spinal cord.

This study quantifies persistent postural and motor deficits after spinal cord injury in mice using unbiased, high-speed video tracking and machine learning.

The paper creates a cross-species spinal cord cell type atlas integrating data from mouse, macaque, and human, identifying conserved and species-specific features.

The paper compares the electrophysiological properties and sensory input organization of CC and Atoh1-lineage neurons in the thoracolumbar spinal cord, finding distinct firing behaviors and input sources despite both receiving proprioceptive information.

The paper defines the anatomical structure of long-range and local proprioceptive circuits in mice, revealing distinct pathways and their functional implications.

The paper determines the birthdates of nociceptor subtypes in mouse DRG neurons, finding continuous birth between E9.5-E13.5 with peak at E10.5-E11.5, and subtype-specific timing.

This study shows that Prdm12 is essential for nociceptor development but not for adult pain sensation, with distinct transcriptional effects in embryonic and adult dorsal root ganglia.

The paper labels intrinsic hand and foot motor neurons using an Atoh1 CRE knock-in mouse line, showing they have a unique developmental history and can be targeted for functional studies.