Author

George Goldenfeld

Scripps Research InstituteORCID 0000-0003-4348-3455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Marco MraviciD· 2 shared Andrew B. WardiD· 1 shared Colleen A. MaillieiD· 1 shared Gerard J. A. KrooniD· 1 shared Jiayi LiiD· 1 shared Minghao ZhangiD· 1 shared Nadia GosietiD· 1 shared Sebastian Jojoa-CruziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Marco MravicORCID

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2 papers

Recent·Most cited

Programmed inhibition of an innate immune receptor via de novo designed transmembrane proteins

Colleen A. Maillie, Minghao Zhang, Nadia Gosiet, George Goldenfeld, Gerard J. A. Kroon, Andrew B. Ward, Marco Mravic

This paper designs synthetic proteins that inhibit TLR4 signaling by binding its transmembrane domain, demonstrating the importance of transmembrane interactions in immune signaling.

Proceedings of the National Academy of Sciences · Sep 22, 2026Peer-reviewedBiochemistry

MemPPI platform for measuring and engineering membrane protein-protein interactions in mammalian cells via split nanoluciferase

Weiyi Tang, Sebastian Jojoa-Cruz, Jiayi Li, George Goldenfeld, Marco Mravic

The paper develops a platform to measure and engineer membrane protein-protein interactions using split nanoluciferase, improving assay accuracy and compatibility with protein engineering.

Protein Science · Feb 12, 2026Peer-reviewedBioengineering