Author

Nadia Gosiet

Scripps Research InstituteORCID 0009-0006-3104-6521Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew B. WardiD· 1 shared Colleen A. MaillieiD· 1 shared George GoldenfeldiD· 1 shared Gerard J. A. KrooniD· 1 shared Marco MraviciD· 1 shared Minghao ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Andrew B. WardORCID

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1 paper

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 22, 2026

Programmed inhibition of an innate immune receptor via de novo designed transmembrane proteins

Colleen A. Maillie, Minghao Zhang, Nadia Gosiet…·Marco Mravic

This paper designs synthetic proteins that inhibit TLR4 signaling by binding its transmembrane domain, demonstrating the importance of transmembrane interactions in immune signaling.

DOI 10.1073/pnas.2536559123

humanprotein structure

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