The Impact of Antimalarial Resistance on the Genetic Structure of Plasmodium falciparum in the DRC
Robert Verity, Özkan Aydemir, Nicholas F. Brazeau, Oliver John Watson, Nicholas J. Hathaway, Melchior Kashamuka Mwandagalirwa, Patrick W. Marsh, Kyaw L. Thwai, Travis M. Fulton, Madeline Denton, Andrew Parker Morgan, Jonathan B. Parr, Patrick K. Tumwebaze, Melissa D. Conrad, Philip Jon Rosenthal, , Jonathan J. Juliano
This study analyzes the genetic structure of Plasmodium falciparum in the DRC, identifying an east-west haplotype divide linked to antimalarial resistance and evidence of gene flow and selection pressures.
Nature Communications · Apr 30, 2020Peer-reviewedGenomics