Author

Stefano Giampiccolo

University of TrentoORCID 0000-0003-4362-246XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2 Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Approach:machine learning (classical)· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Luca MarchettiiD· 4 shared Anna FochesatoiD· 2 shared Federico RealiiD· 2 shared Giovanni IaccaiD· 2 shared Daniele BoarettiiD· 1 shared Elio CampanileiD· 1 shared Elisa PettinàiD· 1 shared Lorena LeonardelliiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersPharmacology & Toxicology

Luca MarchettiORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Pharmacology & ToxicologyMolecular Therapy — Nucleic AcidsPeer-reviewedJul 8, 2026

Physiologically Based Pharmacokinetic Modeling of mRNA-Encoded Therapeutics: A Multiscale Framework for LNP and Antibody Trafficking in Mice

Elio Campanile, Elisa Pettinà, Stefano Giampiccolo…·Luca Marchetti

The paper develops a multiscale pharmacokinetic model integrating mRNA trafficking and antibody disposition in mice, validated with experimental data to predict biodistribution and optimize dosing.

DOI 10.1016/j.omtn.2026.103002

mousebulk RNA-seq

𝕏 PostBluesky

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedMay 27, 2026

A novel approach to quantify out-of-distribution uncertainty in Neural and Universal Differential Equations

Stefano Giampiccolo, Giovanni Iacca, Luca Marchetti

This paper introduces a novel ensemble method for NODEs and UDEs to improve out-of-distribution uncertainty quantification in dynamical systems.

DOI 10.1038/s41540-026-00749-5

statistical modelmachine learning (classical)

𝕏 PostBluesky

Pharmacology & ToxicologyFrontiers in PharmacologyPeer-reviewedJan 8, 2025

stormTB: A web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments.

Roberto Visintainer, Anna Fochesato, Daniele Boaretti…·Luca Marchetti

stormTB provides a web-based mPBPK model for simulating anti-TB drug treatments in mice, enabling pharmacokinetic comparisons and supporting 11 drugs.

1 citation

mouseexperimental assay

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Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedNov 28, 2024

Robust parameter estimation and identifiability analysis with Hybrid Neural Ordinary Differential Equations in Computational Biology

Stefano Giampiccolo, Federico Reali, Anna Fochesato…·Luca Marchetti

The paper introduces a workflow for estimating model parameters and assessing identifiability in hybrid models with partial system knowledge using neural ordinary differential equations.

27 citationstop 5%

statistical modelmachine learning (classical)

𝕏 PostBluesky