Author

Frank Eßmann

Robert Bosch HospitalORCID 0000-0003-4369-8456Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Akshay KanakaniD· 1 shared Alexander PauliD· 1 shared Amro M. AbdelrahmaniD· 1 shared Benjamin SchäferiD· 1 shared Bernhard F. GillisseniD· 1 shared Bishakha Joyeeta SahaiD· 1 shared Dang Quan NguyeniD· 1 shared David William AndrewsiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Akshay KanakanORCID

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2 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedMar 18, 2026

KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival

Thomas L. Ekstrom, Zhangshuai Dai, Julia Thiel…·Steven A. Johnsen

This study identifies KLF5-bound enhancers in pancreatic cancer that regulate cell survival, showing their subtype-independent role in maintaining tumor viability.

2 citationstop 4%

humanATAC-seq

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Molecular BiologyEMBO ReportsPeer-reviewedJul 24, 2024

BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains

Tobias B. Beigl, Alexander Paul, Thomas Fellmeth…·Frank Eßmann

This study identifies a novel interaction between BOK and BCL-2 transmembrane domains that regulates apoptosis and suggests it as a potential drug target.

23 citations

humanexperimental assay

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