Author

Steven A. Johnsen

Robert Bosch HospitalORCID 0000-0003-1198-5805Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Amro M. AbdelrahmaniD· 2 shared Julia ThieliD· 2 shared Mark Joseph TrutyiD· 2 shared Meghana ManjunathiD· 2 shared Meng DongiD· 2 shared Nadine SchachereriD· 2 shared Zeynab NajafovaiD· 2 shared Akshay KanakaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Amro M. AbdelrahmanORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedMar 18, 2026

KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival

Thomas L. Ekstrom, Zhangshuai Dai, Julia Thiel…·Steven A. Johnsen

This study identifies KLF5-bound enhancers in pancreatic cancer that regulate cell survival, showing their subtype-independent role in maintaining tumor viability.

2 citationstop 4%

humanATAC-seq

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Cancer BiologyCell Death DiscoveryPeer-reviewedMar 17, 2026

Epigenetic Context Defines the Transcriptional Activity of Canonical and Noncanonical NF-κB Signaling in Pancreatic Cancer

Joana E. Aggrey-Fynn, Joshua Busch, Dominik Saul…·Steven A. Johnsen

This study identifies TNF and TWEAK as activators of canonical and noncanonical NF-κB signaling in PDAC, revealing distinct epigenetic dependencies of RELA and RELB.

1 citation

humanbulk RNA-seq

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BiochemistryCell Reports MethodsPeer-reviewedJun 1, 2025

CRISPR gene and transcriptome engineering (CRISPRgate) improves loss-of-function genetic screening approaches

Jannis Stadager, Chiara Bernardini, Laura Hartmann…·Philipp Rathert

CRISPRgate improves loss-of-function screening by combining CRISPRko and CRISPRi to enhance gene repression and reduce noise in genetic studies.

5 citations

humanCRISPR screen

𝕏 PostBluesky