Author

Thomas L. Ekstrom

Mayo ClinicORCID 0000-0002-9363-2984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:Hi-C· 1

Frequent Co-Authors

Akshay KanakaniD· 1 shared Alexey V. DvornikoviD· 1 shared Alvin C. H. MaiD· 1 shared Amro M. AbdelrahmaniD· 1 shared Bishakha Joyeeta SahaiD· 1 shared Carla M. ManniD· 1 shared Drena L DobbsiD· 1 shared Emily L. SiegleriD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Akshay KanakanORCID

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2 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedMar 18, 2026

KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival

Thomas L. Ekstrom, Zhangshuai Dai, Julia Thiel…·Steven A. Johnsen

This study identifies KLF5-bound enhancers in pancreatic cancer that regulate cell survival, showing their subtype-independent role in maintaining tumor viability.

2 citationstop 4%

humanATAC-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 16, 2018

Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo

Hirotaka Ata, Thomas L. Ekstrom, Gabriel Martínez‐Gálvez…·Stephen Carl Ekker

This paper demonstrates that inducing Microhomology-mediated End Joining (MMEJ) in vivo can generate highly homogeneous mutant alleles, with a novel algorithm provided for predicting MMEJ-inducing sites.

1 citation

zebrafishCRISPR screen

𝕏 PostBluesky