Poly(ADP-ribose)polymerase1 facilitates the nucleosome disassembly
Aleksandr Andreevich Alekseev, Mikhail M. Kutuzov, Ekaterina A. Belousova…·O. I. Lavrik
The paper shows PARP1 binding weakens nucleosome core contacts using optical tweezers.
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Peter the Great St. Petersburg Polytechnic UniversityORCID 0000-0003-4371-265XUnclaimed ORCID profile · follow to get notified of new preprints
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6 papers
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Aleksandr Andreevich Alekseev, Mikhail M. Kutuzov, Ekaterina A. Belousova…·O. I. Lavrik
The paper shows PARP1 binding weakens nucleosome core contacts using optical tweezers.
Irina V. Bakhlanova, Begoña Carrasco, Aleksandr Andreevich Alekseev…·Dmitry Baitin
This study identifies a single DNA binding site in DprA dimer that facilitates RecA filament nucleation on short ssDNA.
Viktoria Dmitrievna Roshektaeva, Aleksandr Andreevich Alekseev, Alexey Dmitrievich Vedyaykin…·Natalia Evgenevna Morozova
This study uses optical tweezers to investigate RecN's interactions with ssDNA and dsDNA, revealing its predominant ssDNA binding and weak dsDNA binding that forms DNA loop-like structures.
Natalya A. Rumyantseva, Vladimir M. Shutov, Dina G. Belenkaia…·Alexey Dmitrievich Vedyaykin
This study investigates the properties of Ureaplasma parvum SMC ATPase, revealing its ability to compact DNA without ATP, distinct from its Bacillus subtilis homologue.
Viktoria Dmitrievna Roshektaeva, Aleksandr Andreevich Alekseev, Alexey Dmitrievich Vedyaykin…·Natalia Evgenevna Morozova
This study uses fluorescence microscopy and single-molecule techniques to investigate RecN's localization and DNA-binding properties in Escherichia coli.
Aleksandr Andreevich Alekseev, Georgii E. Pobegalov, Natalia Evgenevna Morozova…·Mikhail A. Khodorkovskii
This study investigates how RecX regulates RecA-ssDNA filament conformational states in E. coli, revealing that RecX binds the inactive state and inhibits transition to the active state.