Sara Torstensson

This study creates a single-nuclei transcriptomic atlas of skeletal muscle in women with PCOS, identifying cell-type-specific dysregulation and therapeutic targets.

The paper shows that in a PCOS-like mouse model, altered uterine NK cells contribute to implantation failure through disrupted maturation and compensatory changes in NK cell subsets.

This study shows that androgen exposure in a mouse PCOS model alters immune cell populations in reproductive and metabolic tissues, with effects mediated through androgen receptors.