Marlie M. Maestas

The paper develops a predictive digital model of human pancreatic cell differentiation using single-cell multiomic data to identify regulators and validate their roles in islet fate specification.

This study evaluates dithizone staining for localizing subcutaneously transplanted islets in mice, showing it reliably identifies insulin-producing β-cells and enables consistent dosing.

This study compares the hypoxia response of stem cell-derived and primary human islets using single-cell transcriptomics, revealing divergent metabolic and apoptotic responses.

This study investigates how Coxsackievirus B (CVB) infection affects different cell types in human pancreatic islets using single-cell RNA sequencing, revealing cell-specific transcriptional and functional responses.

This study uses magnetic sorting to enrich human stem cell-derived islets for CD49a, improving β-cell identity and function for diabetes therapy.