NeuroscienceAutophagyPeer-reviewed
BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes
Changyi Ji, Maoping Tang, Claudia Zeidler…·Gail V.W. Johnson
This study shows BAG3 and SYNPO promote autophagy-mediated degradation of phosphorylated MAPT in neuronal synapses, preventing its accumulation and maintaining synaptic health.
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