Author

Zeynab Najafova

Robert Bosch HospitalORCID 0000-0003-4403-5566Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Steven A. JohnseniD· 2 shared Akshay KanakaniD· 1 shared Amro M. AbdelrahmaniD· 1 shared Bishakha Joyeeta SahaiD· 1 shared Chiara BernardiniiD· 1 shared Cristiana LunguiD· 1 shared Emily L. SiegleriD· 1 shared Frank EßmanniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Steven A. JohnsenORCID

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3 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedMar 18, 2026

KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival

Thomas L. Ekstrom, Zhangshuai Dai, Julia Thiel…·Steven A. Johnsen

This study identifies KLF5-bound enhancers in pancreatic cancer that regulate cell survival, showing their subtype-independent role in maintaining tumor viability.

2 citationstop 4%

humanATAC-seq

𝕏 PostBluesky

BiochemistryCell Reports MethodsPeer-reviewedJun 1, 2025

CRISPR gene and transcriptome engineering (CRISPRgate) improves loss-of-function genetic screening approaches

Jannis Stadager, Chiara Bernardini, Laura Hartmann…·Philipp Rathert

CRISPRgate improves loss-of-function screening by combining CRISPRko and CRISPRi to enhance gene repression and reduce noise in genetic studies.

5 citations

humanCRISPR screen

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Molecular BiologybioRxivPreprintMar 13, 2025

PHF19 drives PRC2 sub-nuclear compartmentalization to promote motility in TNBC cells

Nina Pelzer, Teodora Lukic, Wanwan Ge…·Cristiana Lungu

The paper identifies PHF19 as a key factor driving PRC2 sub-nuclear compartmentalization in TNBC cells, linking it to cancer cell motility.

DOI 10.1101/2025.03.13.642950

humanproteomics

𝕏 PostBluesky