Pernille Yde

This paper uses a computational model to show that pancreatic islets can switch between transient and persistent inflammation modes based on feedback loops and islet size.

This paper connects metabolic slowdown to ageing and age-related diseases through a fuel and energy model, explaining anti-ageing interventions and paradoxes of ageing.

The paper explains Gompertzian mortality patterns using a systems model that incorporates inter-dependent subsystems and their temporal failure, providing insights into biological aging and heterogeneity.