Author
Brigham and Women's HospitalORCID 0000-0003-4417-4988Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Dongjing Liu, Dara Meyer, Brian Fennessy…·Alexander W. Charney
The paper investigates the conservation of rare schizophrenia risk variants across diverse populations and finds consistent burden in constrained genes.
Max Lam, Chia‐Yen Chen, Tian Ge…·Todd Lencz
This paper identifies potential nootropic drug targets by integrating large-scale cognitive GWAS and transcriptomic data to find credible druggable genes.
Max Lam, William David Hill, Joey W. Trampush…·Todd Lencz
The paper uses pleiotropic meta-analysis to identify genetic loci associated with cognition, education, and schizophrenia, revealing distinct biological mechanisms for concordant and discordant genetic correlations.
Alexander W. Charney, Eli A. Stahl, Elaine Green…·Pamela B. Sklar
The study finds that rare copy number variants (CNVs) contribute to bipolar disorder risk primarily in schizoaffective disorder bipolar type cases, with differences in CNV burden and schizophrenia polygenic risk scores between subtypes.
Jeanne E. Savage, Philip R. Jansen, Sven Stringer…·Lene Christiansen
This study identifies 206 new genomic loci and 1,041 genes associated with intelligence using a large GWAS meta-analysis of 279,930 individuals.
Gail Davies, Max Lam, Sarah E. Harris…·Luca Kleineidam
This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.
Max Lam, Joey W. Trampush, Jin Yu…·Todd Lencz
This study performs a large-scale GWAS of cognitive ability, identifies 70 genomic loci, and finds tissue-specific gene expression and potential drug targets.