Cancer BiologybioRxivPreprint
Differential Remodeling of the BRCA1 Interactome by a Unique Minimal Clinical Truncation Mutation
Jingjing Chen, Mihaela E. Sardiu, Michaella J. Rekowski…·Roy A. Jensen
The paper identifies how the BRCA1-Y1853ter mutation alters protein interactions and cellular processes, suggesting gain-of-function effects in cancer.
DOI 10.1101/2024.11.26.625539