Xixi Liu

The paper investigates the missense mutation ADNP p.C687R in HVDAS, showing it disrupts chromatin regulation and GABAergic differentiation through gain-of-function mechanisms.

This study uses single-cell RNA-seq to evaluate ACE2 expression in ovarian tissues across developmental stages, identifying high ACE2 expression in PGCs and COC and its potential role in SARS-CoV-2 infection risk.

The paper introduces GeACT, a genomic database for human mid-gestation fetus cells, linking gene expression to chromatin states and identifying key transcription factors.