Jo‐Maree Courtney

This study shows that pericyte ablation in adult mice leads to blood-brain barrier leakage, gliosis, and behavioral changes such as reduced movement and impaired balance.

The paper identifies a subpopulation of microglia associated with pericytes in the brain and shows this population is reduced in Alzheimer's disease in the superior frontal gyrus.

The paper presents an automated method using QuPath to quantify microglia and pericytes in whole mouse brain sections, showing regional differences in cell proportions.