Anna Elizabeth King

This study finds that older adults with subjective cognitive impairment show longer and more variable visuomotor reaction times, suggesting early motor deficits not captured by traditional cognitive tests.

This study shows HDAC6 inhibition with ACY-738 stabilizes microtubules and reduces lower motor neuron degeneration in mSOD1G93A mice, but does not prevent motor function decline.

The paper identifies a subpopulation of microglia associated with pericytes in the brain and shows this population is reduced in Alzheimer's disease in the superior frontal gyrus.

This study uses label-free proteomics to examine temporal changes in microglial protein expression in male and female mice after TBI, finding sex differences in baseline proteomes but not in response over time.

This study examines CLN3 disease using patient-derived cortical neurons, finding reduced electrophysiological activity and lysosomal alterations.

The paper identifies and validates synergistic ligand-receptor pairs that drive astrocyte development in the human brain using computational methods and experimental testing.

This study confirms that combined leptin and pioglitazone treatment reduces Aβ levels more effectively than either drug alone in APP/PS1 mice.

This study develops a self-destructing CRISPR/Cas system for retinal gene editing, showing reduced SpCas9 mRNA and improved safety without compromising on-target efficiency.