Author

Lucia Sedlackova

Barcelona Institute of Science and TechnologyORCID 0000-0003-4482-088XUnclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea Del Carmen-Fabregat· 1 shared Eva Maria NovoaiD· 1 shared Jeremy VicencioiD· 1 shared Kshitij Sinhai· 1 shared Matthias EderiD· 1 shared Natasha OswaliD· 1 shared Nicholas StroustrupiD· 1 shared Oguzhan BegikiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperSystems Biology

Andrea Del Carmen-Fabregat

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1 paper

Recent·Most cited

Systems BiologybioRxivPreprintAug 17, 2026

Declines in mRNA synthesis set the rate of organismal aging

Andrea Del Carmen-Fabregat, Natasha Oswal, Kshitij Sinhai…·Nicholas Stroustrup

The paper shows that declining mRNA synthesis capacity during aging reduces mRNA abundance, driving organismal aging, and that manipulating this decline affects healthspan and lifespan.

DOI 10.64898/2026.07.02.733740

C. elegansmultiome

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