Julica Inderhees

This study identifies ceramide-driven lipotoxicity as a driver of calcific aortic valve disease and shows that SPT inhibition can reverse disease progression in vivo.

This study shows that hepatocyte circadian clocks regulate cholesterol metabolism and protect against MASH, with Bmal1 playing a specific role in this process.

This study investigates how THRB affects diurnal hepatic lipid metabolism in adult male mice, finding THRB deficiency disrupts metabolic rhythms and promotes steatosis.