Jeffrey P. Krischer

imply improves cell-type deconvolution by using personalized reference panels, showing reduced bias and better alignment with biological facts in real data.

The paper introduces a joint model with matching and regularization to detect OTU-specific compositional trajectories predictive of disease onset in metagenomic data.

The paper evaluates the construct validity of PROMIS instruments in osteogenesis imperfecta (OI) and explores using a registry to recruit participants for health status surveys.

The paper identifies shared molecular pathways between ANCA-associated vasculitis and nephrotic syndrome, highlighting JAK-STAT signaling as a potential therapeutic target.