Dejan Lazarević

This study optimizes an ex vivo expansion protocol for mobilized peripheral blood HSCs, enabling robust gene therapy applications with long-term engraftment.

This paper introduces a high-throughput microfluidic platform for organoid culture and multi-omics profiling, demonstrating its utility in clinical and drug discovery settings.

The paper shows that DC-based therapy enhances CD8 T cell responses to neoantigens in lung tumors, particularly in high TMB tumors.

The paper identifies a novel truncating GLI2 variant linked to Culler-Jones syndrome and demonstrates its dominant-negative effect on Hedgehog signaling through functional assays.

The paper uses somatic mutation data from cancers to predict genes involved in germline mutations' phenotypic effects, showing their predictive power is independent of germline-based methods.

The paper uses somatic mutation patterns from cancer to predict genes involved in phenotypic abnormalities and genetic diseases, showing their predictive power is independent of germline-based methods.

This paper sonifies ChIP-seq data of histone modifications into musical scores and shows that the resulting music is perceived as more pleasant than randomized signals, with the waveform predicting phenotypic properties like differential gene expression.