Constantinos Ketonis

Pharmacological Antagonism of Ccr2+ Cell Recruitment to Facilitate Regenerative Tendon Healing

This study shows that temporarily blocking Ccr2+ cell recruitment during the late inflammatory/early proliferative phase improves tendon healing mechanics, while blocking during the acute phase has no effect.

Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

This study shows that suppressing IKKβ/NF-κB in Scleraxis-lineage cells during tendon healing increases scar tissue and apoptosis.