Gaëlle Philippin

The paper shows that the RecBC complex protects nascent DNA from degradation by ExoI during lesion bypass, ensuring efficient repair of single-stranded DNA gaps.

This study shows that a unique secondary contact of Pol IV with the processivity clamp enhances its ability to perform translesion synthesis past strong replication blocks.

The paper shows that the presynaptic phase is crucial for modulating lesion tolerance pathways in E. coli, with defects leading to reduced HDGR and increased TLS.

This paper identifies a non-catalytic role of RecBCD in stabilizing blocked replication forks during homology directed gap repair and translesion synthesis.