Lara Lee

A systematic interactome of SET1C expands its functional landscape and identifies candidate regulatory connections

The paper identifies new interactors of the SET1C complex through yeast two-hybrid screens, revealing its roles in chromatin regulation, RNA biogenesis, and nuclear transport.

Extending the gap and loading RecA: the presynaptic phase plays a pivotal role in modulating lesion tolerance pathways

The paper shows that the presynaptic phase is crucial for modulating lesion tolerance pathways in E. coli, with defects leading to reduced HDGR and increased TLS.

UFMylation of MRE11 is essential for telomere length and hematopoietic stem cell survival

The paper identifies UFMylation of MRE11 as critical for telomere length and hematopoietic stem cell survival, showing its role in telomere maintenance without affecting DNA repair.

A non-catalytic role of RecBCD in Homology Directed Gap Repair and Translesion Synthesis

This paper identifies a non-catalytic role of RecBCD in stabilizing blocked replication forks during homology directed gap repair and translesion synthesis.