Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-7863-4922Unclaimed ORCID profile · follow to get notified of new preprints
9 papers
Recent·Most cited
Gaëlle Philippin, Dupaigne Pauline, Élodie Chrabaszcz, Maialen Iturralde, Mauro Modesti, Éric Le Cam, Vincent Pagès, Luisa Laureti
The paper shows that the RecBC complex protects nascent DNA from degradation by ExoI during lesion bypass, ensuring efficient repair of single-stranded DNA gaps.
Proceedings of the National Academy of Sciences · Sep 10, 2025Peer-reviewedMolecular Biology
Seungwoo Chang, Luisa Laureti, Elizabeth S. Thrall, Marguerite S. Kay, Gaëlle Philippin, Slobodan Jergic, Vincent Pagès, Joseph J. Loparo
This study shows that a unique secondary contact of Pol IV with the processivity clamp enhances its ability to perform translesion synthesis past strong replication blocks.
Proceedings of the National Academy of Sciences · Feb 24, 2025Peer-reviewedBiochemistry
Drago Haas, Matthieu Barba, Cláudia M. Vicente, Šarká Nezbedová, Amélie Garénaux, Stéphanie Bury‐Moné, Jean-Noël Lorenzi, Laurence Hôtel, Luisa Laureti, Annabelle Thibessard, Géraldine Le Goff, Jamal Ouazzani, Pierre Leblond, Bertrand Aigle, Jean‐Luc Pernodet, , Sylvie Lautru
SYNTERUPTOR identifies genomic islands containing specialised metabolite gene clusters in microbial genomes, detecting clusters missed by existing tools.
NAR Genomics and Bioinformatics · Apr 4, 2024Peer-reviewedBioinformatics
Luisa Laureti, Lara Lee, Gaëlle Philippin, Michel Kahi, Vincent Pagès
The paper shows that the presynaptic phase is crucial for modulating lesion tolerance pathways in E. coli, with defects leading to reduced HDGR and increased TLS.
PLoS Genetics · Jun 2, 2022Peer-reviewedMolecular Biology
Jean-Hugues Guervilly, Marion Blin, Luisa Laureti, Émilie Baudelet, Stéphane Audebert, Pierre-Henri L. Gaillard
This study identifies a novel function of SLX4 in inhibiting MutSα-dependent mismatch repair through its interaction with MSH2.
Nucleic Acids Research · Jan 25, 2022Peer-reviewedMolecular Biology
Katarzyna H. Masłowska, Florencia Villafañez, Luisa Laureti, Shigenori Iwai, Vincent Pagès
The paper shows TLS is locally controlled by PCNA ubiquitination at individual lesions, not globally induced by genotoxic stress.
Nucleic Acids Research · Jan 14, 2022Peer-reviewedMolecular Biology
Katarzyna H. Masłowska, Luisa Laureti, Vincent Pagès
The paper introduces a method to insert modified DNA into the yeast genome and shows how DNA damage tolerance is regulated by inhibiting homologous recombination.
Nucleic Acids Research · Aug 7, 2019Peer-reviewedMolecular Biology
Élodie Chrabaszcz, Luisa Laureti, Vincent Pagès
The paper shows that proximity of replication-blocking lesions in E. coli increases error-prone TLS usage, independent of SOS activation, but additive with SOS mutagenic effects.
Nucleic Acids Research · Feb 13, 2018Peer-reviewedMolecular Biology
Luisa Laureti, Lara Lee, Gaëlle Philippin, Vincent Pagès
This paper identifies a non-catalytic role of RecBCD in stabilizing blocked replication forks during homology directed gap repair and translesion synthesis.
Nucleic Acids Research · Mar 24, 2017Peer-reviewedMolecular Biology