Author

Denise Winkler

Ludwig-Maximilians-Universität München

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:Arabidopsis· 1 Approach:deep learning· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Bachuki ShashikadzeiD· 3 shared Bjoern Schwalb· 3 shared Henrik DaubiD· 3 shared Martin StegeriD· 3 shared Patrick R. A. ZanoniD· 3 shared Uli OhmayeriD· 3 shared Anastasia Bednarz· 2 shared Denis Bartoschek· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

Bachuki ShashikadzeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery of CDK4-selective molecular glue degraders by high-throughput proteomics

Patrick R. A. Zanon, Bachuki Shashikadze, Denise Winkler, Ines F. Scheller, Denis Bartoschek, Anastasia Bednarz, Tobias Graef, Sophie Machata, Uli Ohmayer, Bjoern Schwalb, Martin Steger, Henrik Daub

This study identifies a CDK4-selective molecular glue degrader, NE26394, using high-throughput proteomics, showing its efficacy in CDK4-dependent cancer models.

bioRxiv · Jun 22, 2026 · PreprintBiochemistry

Integrated proteomic screening reveals design principles of CRBN molecular glue degraders

Bachuki Shashikadze, Ines F. Scheller, Denise Winkler, Patrick R. A. Zanon, Anastasia Bednarz, Denis Bartoschek, Sophie Machata, Tobias Graef, Uli Ohmayer, Bjoern Schwalb, Henrik Daub, Martin Steger

The paper identifies new CRBN neosubstrates using proteomic screening and machine learning, expanding the landscape of molecular glue degraders.

bioRxiv · Mar 10, 2026 · PreprintBiochemistry

Developing Potent and Selective TBK1 Molecular Glue Degraders for Cancer Immunotherapy

John Caldwell, Patrick R. A. Zanon, Iona Ferguson, Stephen T. Hallett, Tencho Tenev, Natalia Serrano-Aparicio, Russell J.H. Wood, Shakil Khan, Sidonie Wicky John, Rebecca Wilson, Matthew T. Warren, P. Craig McAndrew, Martin Steger, Denise Winkler, Uli Ohmayer, , Zoran Ranković

This paper develops a first-in-class TBK1 molecular glue degrader, CCT412020, which enhances anti-tumour immunity and overcomes immune checkpoint blockade resistance.

bioRxiv · Feb 2, 2026 · PreprintCancer Biology

Role of Chloroplast Lipid-Remodelling Protein 23 During Cold Acclimation in Arabidopsis thaliana

Wing Tung Lo, Denise Winkler, Maximilian Münch, Martin Lehmann, Kira Steiner, Bettina Bölter, Cornelius Gamb, Cecilia Tullberg, Carl Grey, Tatjana Kleine, Eslam M. Abdel-Salam, Katharina W. Ebel, H. Ekkehard Neuhaus, Deren Büyüktaş, Sophie de Vries, , Serena Schwenkert

This study investigates the role of CLRP23 in cold acclimation of Arabidopsis thaliana, showing its involvement in lipid remodeling and integration of membrane and metabolic responses.

bioRxiv · Jul 22, 2025 · PreprintPlant Biology