Andrei N. Lukashkin

This paper investigates how a Connexin 30 mutation affects cochlear electrophysiology, showing it rescues high-frequency hearing loss while impairing low-frequency hearing through changes in gap junction coupling and potassium currents in Deiters cells.

This study shows that a gap-junction mutation in mice preserves high-frequency hearing by maintaining extracellular receptor potentials in outer hair cells, suggesting these potentials drive cochlear amplification at high frequencies.

This paper demonstrates that low-frequency round window micro vibrations enhance drug distribution along the cochlea without breaching boundaries, suggesting potential for improved drug delivery in hearing loss treatments.

The paper introduces a method for uniform drug delivery across the entire cochlea without disrupting its boundaries, overcoming concentration gradient issues.