Author

Tom Z. Yuan

Twist Bioscience (United States)ORCID 0000-0003-4585-8943Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aaron K. SatoiD· 2 shared Ana González HernándeziD· 1 shared Anamika B. PateliD· 1 shared Ben KrauseiD· 1 shared Eric A. OrtlundiD· 1 shared Fumiko T. Axelrod· 1 shared Marisa L. YangiD· 1 shared Nikhil NaikiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

Aaron K. SatoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 2, 2024

Structural basis of SARS-Cov-2 spike recognition by engineered synthetic multivalent VHH antibodies

Ana González Hernández, Zane T. Laughlin, Anamika B. Patel…·Aaron K. Sato

The paper describes the engineering of synthetic multivalent VHH antibodies against SARS-CoV-2 spike protein and shows how mutations affect their binding.

DOI 10.1101/2024.10.02.616254

proteomicsexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintSep 13, 2023

Improving antibody affinity using laboratory data with language model guided design

Ben Krause, Subu K. Subramanian, Tom Z. Yuan…·Nikhil Naik

The paper fine-tunes language models on laboratory data to design antibodies with improved affinity, achieving sub-25 picomolar binding for four antibodies.

3 citations

proteomicsmachine learning (classical)

𝕏 PostBluesky