Sandy Al Hayek

This study shows that splice-switching ASOs targeting V exons in myeloma cells induce selective plasma cell clone death via ER stress and apoptosis.

This study shows that Svb, an OvoL factor in Drosophila, integrates signaling inputs to regulate intestinal stem cell self-renewal and differentiation through post-translational processing and context-dependent transcriptional activity.

This study identifies Shavenbaby as a novel Hippo pathway effector critical for adult stem cell survival by activating DIAP1 to prevent apoptosis in Drosophila renal stem cells.