François Payre

This study shows that cancer cachexia in Drosophila reduces sex-specific differences in gene expression and metabolic profiles, leading to a shared molecular cachexic state.

The paper investigates the spatiotemporal requirements for transcription activation by analyzing enhancer-promoter interactions in living Drosophila embryos using transvection and 3D imaging.

The paper identifies Pri smORF peptides as pleiotropic regulators of leg development in Drosophila, functioning through Ubr3-dependent and -independent mechanisms in patterning and cell survival.

The paper identifies how Shavenbaby isoforms regulate gene expression and chromatin structure during Drosophila intestinal stem cell differentiation.

This study shows that Svb, an OvoL factor in Drosophila, integrates signaling inputs to regulate intestinal stem cell self-renewal and differentiation through post-translational processing and context-dependent transcriptional activity.

This study identifies Shavenbaby as a novel Hippo pathway effector critical for adult stem cell survival by activating DIAP1 to prevent apoptosis in Drosophila renal stem cells.

The paper identifies an ancestral developmental module involving micropeptides and transcription factors that regulates insect embryonic patterning, showing functional plasticity despite evolutionary divergence.