GeneticsbioRxivPreprint
Different alterations in mRNP composition trigger an increase in harmful R-loops
José Antonio Mérida-Cerro, Guillaume Chevreux, Benoı̂t Palancade…·Andrés Aguilera
The paper identifies RNA-binding proteins and mRNP assembly perturbations that lead to R-loop accumulation and DNA damage, linking these processes to cancer and neurodegenerative diseases.
DOI 10.1101/2024.11.11.622913