NeurosciencebioRxivPreprint
G51D mutation of the endogenous rat Snca gene disrupts synaptic localisation of α-synuclein priming for Lewy-like pathology
Stephen West, Ammar Natalwala, Karamjit Singh Dolt…·Tilo Kunath
This study introduces a G51D mutation in the rat Snca gene, leading to synaptic mislocalization of α-synuclein and increased susceptibility to Lewy-like pathology.
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