Kim T. Blackwell

This study shows that calmodulin regulates calcium dynamics in neurons by modulating RyR2 and PMCA, with implications for aging and Alzheimer's disease.

The paper uses computational modeling and post-mortem gene expression data to show that schizophrenia-associated genes impair PKA-mediated LTP in GluR1-containing synapses, linking genetic factors to synaptic plasticity deficits.

The paper shows that synaptic plasticity is robust to trial-to-trial variability and is controlled by spatiotemporal firing rate patterns using a computational model.

The paper develops a computational model to show how different temporal stimulation patterns select specific signaling pathways for ERK activation during L-LTP induction.

This study shows that endocannabinoids and dopamine interact to modulate long-term plasticity in the entopeduncular nucleus, influencing the balance of direct and indirect output dominance.

The paper develops a biochemically detailed computational model of cortical post-synaptic plasticity that integrates multiple signalling pathways and reproduces observed plasticity phenomena.