Author

Akira Takeda

University of TurkuORCID 0000-0003-4748-4543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Sirpa JalkaneniD· 3 shared Anni KaukoiD· 1 shared Anton V. ZavialoviD· 1 shared Christa E Muller· 1 shared Corinna WeileriD· 1 shared Denis ĐermadiiD· 1 shared Diana LehotinaiD· 1 shared Dominik EichiniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

Sirpa JalkanenORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 13, 2026

Adenosine impairs T cell function via activation of purine salvage pathway and AMP-induced inhibition of pyrimidine nucleotide biosynthesis

Karolina Losenkova, Ursula J Von Danwitz, Nora Kreisig…·Gennady G. Yegutkin

This study shows adenosine impairs T cell function by activating the purine salvage pathway and inhibiting pyrimidine biosynthesis through AMP-mediated suppression of UMP synthase.

DOI 10.64898/2026.09.07.749884

humanflow cytometry

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ImmunologyNature CommunicationsPeer-reviewedNov 17, 2025

Breast Cancer Remodels Lymphatics in Sentinel Lymph Nodes

Dominik Eichin, Diana Lehotina, Anni Kauko…·Sirpa Jalkanen

This study identifies changes in lymphatic endothelial cell subsets and increased MGP expression in metastatic sentinel lymph nodes from breast cancer patients.

11 citationstop 4%

humanscRNA-seq

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Systems BiologyFrontiers in Cardiovascular MedicinePeer-reviewedApr 30, 2020

A single-cell transcriptional roadmap of the mouse and human lymph node lymphatic vasculature

Menglan Xiang, Rubén Adrián Grosso, Akira Takeda…·Eugene C. Butcher

This paper uses single-cell transcriptomics to map the transcriptional organization of lymphatic endothelial cells in mouse and human lymph nodes, identifying distinct subsets and their functional roles.

147 citationstop 2%

mousehuman

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