BiophysicsbioRxivPreprint
Structural basis for hydrolytic splicing of a circularly permuted group II intron
Xiaobin Ling, Yuqi Yao, Dmitrij Golovenko…·Jinbiao Ma
This study presents cryo-EM structures of a circularly permuted group II intron, revealing the mechanism of the hydrolysis pathway and its regulation by branch point and splice site mutations.
DOI 10.64898/2025.12.30.696962