Jinbiao Ma

Structural basis for hydrolytic splicing of a circularly permuted group II intron

This study presents cryo-EM structures of a circularly permuted group II intron, revealing the mechanism of the hydrolysis pathway and its regulation by branch point and splice site mutations.

HGNNPIP: A Hybrid Graph Neural Network framework for Protein-protein Interaction Prediction

HGNNPIP improves PPI prediction by addressing data bias through a hybrid graph neural network framework, outperforming existing methods on benchmark datasets.

A Small Subset of Cytosolic dsRNAs Must Be Edited by ADAR1 to Evade MDA5-Mediated Autoimmunity

MyoD is a structure organizer of 3D genome architecture in muscle cells

The paper shows MyoD organizes 3D genome architecture in muscle cells and demonstrates H3K27ac is insufficient for MyoD-induced chromatin loops.

A Pandas complex adapted for piRNA-guided transposon silencing

The paper identifies a ternary complex involving Panx, dNxf2, and dNxt1 that suppresses transposon expression by inhibiting RNA export.