Author

Shinobu Kitazume

Fukushima Medical UniversityORCID 0000-0003-4757-723XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Yuriko Tachida· 2 shared Akihiro ShindoiD· 1 shared Daisuke Takakura· 1 shared Hideaki Suzuki· 1 shared Hidekazu Tomimoto· 1 shared Hiroshi ManyaiD· 1 shared Hiroyuki TakuwaiD· 1 shared Junko Iijima· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Yuriko Tachida

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 20, 2022

Non-classical glycosylation determines intracellular trafficking of APP and Aβ production

Yuriko Tachida, Junko Iijima, Kazuto Takahashi…·Shinobu Kitazume

The paper investigates how non-classical O-glycosylation of APP affects its trafficking and Aβ production in endothelial cells, linking it to CAA pathology.

DOI 10.1101/2022.06.20.496769

mouseprotein sequence

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NeurosciencebioRxivPreprintJul 22, 2020

Endothelial expression of human APP leads to cerebral amyloid angiopathy in mice

Yuriko Tachida, Saori Miura, Rie Imamaki…·Shinobu Kitazume

This study shows that expressing human APP in endothelial cells of mice leads to cerebral amyloid angiopathy, highlighting the role of both neuronal and endothelial APP in vascular Aβ deposition.

1 citation

mouseexperimental assay

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