Author

Yuriko Tachida

RIKEN

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Shinobu KitazumeiD· 2 shared Akihiro ShindoiD· 1 shared Daisuke Takakura· 1 shared Hideaki Suzuki· 1 shared Hidekazu Tomimoto· 1 shared Hiroshi ManyaiD· 1 shared Hiroyuki TakuwaiD· 1 shared Junko Iijima· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Shinobu KitazumeORCID

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2 papers

Recent·Most cited

Non-classical glycosylation determines intracellular trafficking of APP and Aβ production

Yuriko Tachida, Junko Iijima, Kazuto Takahashi, Hideaki Suzuki, Yoshiki Yamaguchi, Katsunori Tanaka, Miyako Nakano, Daisuke Takakura, Nana Kawasaki, Yuko Saito, Hiroshi Manya, Tamao Endo, Shinobu Kitazume

The paper investigates how non-classical O-glycosylation of APP affects its trafficking and Aβ production in endothelial cells, linking it to CAA pathology.

bioRxiv · Jun 20, 2022 · PreprintNeuroscience

Endothelial expression of human APP leads to cerebral amyloid angiopathy in mice

Yuriko Tachida, Saori Miura, Rie Imamaki, Naomi Ogasawara, Hiroyuki Takuwa, Naruhiko Sahara, Akihiro Shindo, Yukio Matsuba, Takashi Saito, Naoyuki Taniguchi, Yasushi Kawaguchi, Hidekazu Tomimoto, Takaomi C. Saido, Shinobu Kitazume

This study shows that expressing human APP in endothelial cells of mice leads to cerebral amyloid angiopathy, highlighting the role of both neuronal and endothelial APP in vascular Aβ deposition.

bioRxiv · Jul 22, 2020 · PreprintNeuroscience