Author

David N. Beratan

Duke UniversityORCID 0000-0003-4758-8676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander N. VolkoviD· 1 shared Gessica M. Adornato· 1 shared Hyunil JoiD· 1 shared Ivan V. KorendovychiD· 1 shared Peng LiuiD· 1 shared Sagar BhattacharyaiD· 1 shared Wael El Yazidi Mouloud· 1 shared William F. DeGradoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alexander N. VolkovORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 10, 2026

Interplay of stability and dynamics in the optimization of a highly proficient de novo enzyme

Sagar Bhattacharya, Gessica M. Adornato, Yuda Chen…·William F. DeGrado

This study identifies features contributing to catalytic efficiency in a de novo enzyme through computational design and directed evolution, showing how stability and dynamics interplay in enzyme optimization.

DOI 10.64898/2026.05.29.728685

proteomicsexperimental assay

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