Author

Cheng Cheng Zhang

The University of Texas Southwestern Medical CenterORCID 0000-0003-4763-3887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Andrew Young KohiD· 1 shared Bruce A. PosneriD· 1 shared Chen LiaoiD· 1 shared Christina M. ZarekiD· 1 shared Erdal ToprakiD· 1 shared Fatma Neslihan KalkaniD· 1 shared Hesuiyuan Wang· 1 shared Indu RamaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Andrew Young KohORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 19, 2026

A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8+ T cell antitumor immunity

Wenling Li, Christina M. Zarek, Hesuiyuan Wang…·Andrew Young Koh

This study identifies TDCA, a microbiota-derived bile acid, as a mediator that restores immune checkpoint therapy efficacy after antibiotic-induced hyporesponsiveness by enhancing CD8+ T cell antitumor immunity.

1 citation

mouseproteomics

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Cancer BiologyScientific ReportsPeer-reviewedJun 3, 2025

Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

Fatma Neslihan Kalkan, Muhammed Sadik Yildiz, N. Ezgi Wood…·Erdal Toprak

This study investigates drug-drug interactions in AML cell lines, finding widespread but non-conserved synergistic and antagonistic effects across different cell lines.

7 citations

humanexperimental assay

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