Jennifer M. Bomberger

The paper identifies positively selected codon changes in exsA or exsD that hyperactivate the T3SS in P. aeruginosa, leading to hypervirulence through increased T3SS activity and immunopathology.

This study shows that host-secreted lactate from viral-infected airway epithelial cells reduces macrophage antibacterial activity by reprogramming their metabolism.

This study finds that respiratory viral infections increase Pseudomonas abundance in cystic fibrosis airways, with persistent microbial changes and associations with pro-inflammatory cytokines.

This study investigates how lytic bacteriophages interact with respiratory epithelial cells and their effects on cytokine secretion, highlighting the need to consider mammalian responses in phage therapy.

SprayNPray provides a user-friendly tool for taxonomic profiling of genome and metagenome contigs using multiple metrics to classify and analyze sequences.